May Canady is a strange young woman.  Born with a lazy eye which leads to her becoming an outcast at school, and having grown up with an overprotective mother, May is a shy, socially awkward girl with no friends - aside from the collectible doll her mother gave her when she was a young girl.  She works at a veterinary clinic during the day with Polly, (Anna Faris, in an odd and quirky performance), a nymphomaniac lesbian who is not-so-subtlety trying to seduce her.  She also volunteers to watch blind kids at a day care facility.

One day on her way into work she notices Adam (Jeremy Sisto) and immediately develops a crush on him, though it's mostly because she says his hands are beautiful.  Adam is a brooding mechanic who says he "likes weird" - he attends Argento films and has a weird collection of photographs and other strange memorabilia in his room.  However, once Adam becomes aware of the extent of May’s eccentricities, he leaves her, and she subsequently starts using the advice her mother gave her, that "if you can't find a friend, make one."

From there, the film explores May's descent into insanity, alternating from tongue-in-cheek and black comedy to genuinely horrifying and chilling scenes.  This film, written and directed by Lucky McKee, is a refreshing take on the tired horror film industry, which had long been surviving on teen slashers or spoofs with no real depth or genuine scares.

One great thing about May is that it doesn’t seem to take itself too seriously.  There are some truly funny moments in this film, and while at times it can seem to be a bit confused ? you don't know whether you're supposed to be laughing or cringing ? for the most part, it works.

Angela Bettis as the title character gives one of the best performances I've ever seen in a horror movie.  She's awkward and shy and it's chilling to watch her become so intense and creepy over the course of two hours.  She plays May perfectly, and is amazing in every scene.  Bettis is given a wide range of emotions to deal with throughout the film, there are some honestly heartbreaking moments, as well as offbeat comedy, and Bettis plays each scene very well.

Jeremy Sisto as Adam does a passable job as May's crush.  He's interesting to watch throughout the film and adds to its weirdness.

Overall, May is one of the most inventive horror films I've ever seen.  It's clearly influenced by Argento, and even such films as Carrie (it's worth noting that Bettis went on to star in the made-for-tv version of the Stephen King novel) without overtly stealing anything from its predecessors; it uses its material in an original way.  I don't really have any complaints about this movie except for a few confusing scenes where the message wasn't very clear.  It's a definite must-see.